Assessment Of Dietary Exposure Of Tetracyclines In Chicken Meat From Certified Chicken Processing Plants In Malaysia

Marzura, M.R. , Khairunnisak, M., Marni, S. & Saipul B.A.R.

Marzura, M.R. , Khairunnisak, M., Marni, S. & Saipul B.A.R.

Dietary exposure assessment to tetracycline drugs was conducted by multiplying mean residue concentration with mean chicken consumption, also incorporating the processing factor. Residue concentration data was taken from the Monitoring and Surveillance Program of Department of Veterinary Services from year 2010-2015, involving 224 chicken meat samples collected from chicken processing plants throughout Malaysia. The chicken consumption data was based on the Malaysian Adult Nutrition Survey 2014 report. The processing factor used for tetracycline (TTC) and oxytetracycline (OTC) was 0.5, whereas chlortetracycline (CTC) and doxycycline (DC) was 0.1. The highest mean concentration of residue in chicken samples was OTC at 83.7 ?g/kg, followed by DC (80.6 ?g/kg), CTC (46.7 ?g/kg) and TTC (42.2 ?g/kg). Mean chicken consumption for Malaysian adults aged 18-59 years old was 34.95 g, whereas 118.00 g at 97.5th percentile. In all cases, the exposure was always highest in OTC, due to the high mean residue found in chicken samples. Among geographical zones, exposure was highest in East Malaysia compared to Peninsular Malaysia (2.9 and 2.6 ?g/person/day). Overall, the sum of exposure to tetracycline drugs among adults in Malaysia in the current study was 2.6 ?g/person/day, whereas 8.9 ?g/person/day at 97.5th percentile (heavy users), and could be considered negligible (less than 1% Acceptable Daily Intake).